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Beacon Hill
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Research Scientist - Cell Based Assays

Beacon Hill · South San Francisco, CA

Actively hiring Posted 7 months ago

We are seeking a highly motivated and experienced research scientist to support assay development and execution. The ideal candidate will have demonstrated expertise in high throughput/plate-based formats (e.g., CTG, HTRF, NanoBRET), microscopy, and laboratory automation. This role requires hands-on lab experience.

Responsibilities:

  • Perform weekly cell-biological assays for screening cascades and prepare associated data reports
  • Develop and implement cell-based assays using diverse approaches, such as viability, reporter genes, and target engagement/MoA for candidate drugs (e.g., fluorescence microscopy, NanoDLR, NanoBRET)
  • Generate statistics and reports using experimental curve-fitting tools (e.g., GraphPad PRISM, CDD)
  • Contribute to multiple projects in parallel, balancing duties across project teams
  • Perform all duties in alignment with core values, internal policies, and applicable regulations

Requirements
:

  • PhD (0+/2) or MS degree with 6+ years of industry experience in a relevant biological or scientific discipline
  • Extensive experience in mammalian cell culture
  • Hands-on experience performing and developing plate and cell-based assays
  • Strong troubleshooting, organization, and planning skills
  • Excellent oral and written communication skills
  • Background in small molecule drug discovery and development, or relevant academic experience
  • Experience in microscopy, lab automation, and/or programming for data analysis is a plus
  • Experience externalizing assays and managing CROs is a plus

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